Carbonylhydridotris(triphenylphosphine)rhodium(I)

Synonym : Carbonyltris(triphenylphosphine)rhodium(I) Hydride

Synonym : Tris(triphenylphosphine)rhodium(I) Carbonyl Hydride

General Information
TCI Product No. : C1383
Stock Status :
Unit Sizes Price Available stock
Belgium Tokyo *
1G 97.15 EUR 2 >10
5G 375.00 EUR 2 >10

Status at 03:00 a.m. on 04 Feb 2012

* Items available from stock in Japan will be delivered in 10 business days
Purity / Analysis Method :
Storage :
M.F. / M.W. : C55H46OP3Rh=918.80
CAS Number : 17185-29-4
Related CAS Number :
MDL Number : MFCD00151644
Application

Rh(I)-catalyzed synthesis of indoles through the amino-Claisen rearrangement of N-propargylanilines

Rh(I)-catalyzed synthesis of indoles through the amino-Claisen rearrangement of N-propargylanilines

Typical procedure: Under an argon atmosphere, to a solution of carbonyltris(triphenylphosphine)rhodium(I) hydride (16 micro-mol) in 1,1,1,3,3,3-hexafluoro-2-propanol (1 mL) is added N-2-butynyl-N-benzyl-4-methoxyaniline (0.4 mmol) in 1,1,1,3,3,3-hexafluoro-2-propanol (1.5 mL) at an ambient temperature, and the mixture is refluxed until the consumption of the substrate by TLC analysis. The mixture is diluted with ether and filtered through a Celite pad. After concentration of the filtrate to dryness, purification by silica gel chromatography (hexane/AcOEt = 25:1) gives the corresponding indole in 99% yield.
References
Merck Index(14) : 9758
F & F : 7, 53
EC Number : 241-230-3
Transport Information
UNNo. : 2811
Class : 6.1
PG : III
Safety
Signal Word : Danger
Pictogram : Skull and Crossbones
GHS H Statement : Toxic by inhalation, in contact with skin and if swallowed.
GHS P Statement : IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse mouth. IF ON SKIN: Gently wash with plenty of soap and water. Avoid breathing. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician. Wash hands thoroughly after handling.
Risk Phrases
R20/21/22 : Harmful by inhalation, in contact with skin and if swallowed.
Safety Phrases
S22 : Do not breathe dust.
S36/37 : Wear suitable protective clothing and gloves.
Informative Links
Related Categories :
Structure of Chemicals Classes of Metal Compounds Transition Metal Compounds Rh (Rhodium) Compounds
Synthetic Organic Chemistry Catalysts for Organic Synthesis Homogeneous Catalysts Metal Complexes
Synthetic Organic Chemistry Catalysts for Organic Synthesis Homogeneous Catalysts Rhodium

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