Structure
| TCI Product No. : | D1601 | ||||||||||||||||||
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| Stock Status : |
Status at 03:00 a.m. on 08 Feb 2012 * Items available from stock in Japan will be delivered in 10 business days |
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| Purity / Analysis Method : | >98.0%(T) | ||||||||||||||||||
| Storage : | Refrigerator | ||||||||||||||||||
| M.F. / M.W. : | C8H17N3.HCl=191.70 | ||||||||||||||||||
| CAS Number : | 25952-53-8 | ||||||||||||||||||
| Related CAS Number : | |||||||||||||||||||
| MDL Number : | MFCD00012503 | ||||||||||||||||||
| mp : | 115 °C |
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Water-soluble Condensation Reagent Typical Procedure: To a 50 mL round bottom flask equipped with a magnetic stir bar and septum is added 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 2.54 g (13.3 mmol), 4-dimethylaminopyridine 1.62 g (13.3 mmol), carboxylic acid 1.02 g (2.46 mmol), alcohol 0.96 g (3.98 mmol) and CHCl3 (15 mL), and the reaction mixture is stirred at room temperature for 2.5 days. Acetic acid (0.5 mL) is added and the reaction mixture is stirred for 10 min to convert excess alcohol to a more easily separable acetate. The mixture is washed with saturated aqueous NH4Cl solution, diluted with Et2O, and the layers are dried, filtered and concentrated under reduced pressure. The crude material is chromatographed by silica gel column chromatography (hexane：ethyl acetate = 9：1) to give the desired product 1.25 g (1.96 mmol, 80%). |
| RTECS# : | FF2200000 |
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| EC Number : | 247-361-2 |
| Signal Word : | Warning |
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| Pictogram : |
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| GHS H Statement : | Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. |
| GHS P Statement : | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF ON SKIN: Gently wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention. Wash hands thoroughly after handling. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. If eye irritation persists: Get medical advice/attention. |
| R36/37/38 : | Irriterer øynene, luftveiene og huden. |
| S26 : | Får man stoffet i øynene, skyll straks grundig med store mengder vann og kontakt lege. |
| S37/39 : | Bruk egnede vernehansker og -briller/ansikts- sjerm. |
| Related Categories : |
Synthetic Organic Chemistry
Condensation & Active Esterification
Biochemistry Peptide Synthesis Liquid Phase Peptide Synthesis Coupling Reactions (Peptide Synthesis) Biochemistry Sugars Reagents for Oligosaccharide Synthesis Biochemistry Bioconjugation Linkers Zero-length Crosslinkers |
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