N-Fluoro-N'-(chloromethyl)triethylenediamine Bis(tetrafluoroborate)

Synonym : 1-(Chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane Bis(tetrafluoroborate)

Certificate of Analysis

About Lot Numbers

MSDS[PDF]

General Information

TCI Product No. :

F0358

Stock Status :

Status at 03:00 a.m. on 07 Feb 2012

* Items available from stock in Japan will be delivered in 10 business days

Purity / Analysis Method :

>90.0%(T)

Storage :

M.F. / M.W. :

C7H14B2ClF9N2=354.26

CAS Number :

140681-55-6

Related CAS Number :

MDL Number :

MFCD00142607

Application
Regioselective Fluorohydroxylation Reaction of Arylallenes C. Zhou, J. Li, B. Lu, C. Fu, S. Ma, Org. Lett., 2008, 10, 581. Regiospecific fluorination of functionalized phenols Typical procedue: To 4-(biphenyl)tributylstananne (44.3 mg) in acetone (2.0 mL) at 23ºC is added silver triflate (51.4 mg) and N-fluoro-N'-(chloromethyl)triethylenediamine bis(tetrafluoroborate) (F-TEDA-BF4) (42.5 mg). The reaction mixture is stirred for 20 min at 23ºC and then concentrated in vacuo. The residue is purified by preparative TLC eluting with hexane to give 12.0 mg of the fluorinated compound as colorless solid (70% yield). T. Furuya, A. E. Strom, T. Ritter, J. Am. Chem. Soc. 2009, 131, 1662.

References
Merck Index(14) :	8425

Safety
Signal Word :	Danger
Pictogram :
GHS H Statement :	Harmful if swallowed. Causes serious eye damage. May cause an allergic skin reaction. Harmful to aquatic life with long lasting effects.
GHS P Statement :	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF ON SKIN: Gently wash with plenty of soap and water. Avoid breathing. Avoid release to the environment. If skin irritation or rash occurs: Get medical advice/attention. Wash hands thoroughly after handling.

Risk Phrases
R22 :	Farlig ved svelging.
R34 :	Etsende.

Safety Phrases
S22 :	Unngå innånding av støv.
S26 :	Får man stoffet i øynene, skyll straks grundig med store mengder vann og kontakt lege.
S36/37/39 :	Bruk egnede verneklær, -hansker og -briller/ansikts- sjerm.
S45 :	Ved uhell eller illebefinnende er omgående legebehandling nødvendig, vis etiketten hvis mulig.

Informative Links
TCI Product Literature :	Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds[PDF]
Related Categories :	Structure of Chemicals B (Classes of Boron Compounds) Tetrafluoroborates Synthetic Organic Chemistry Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds Fluorinating Reagents Electrophilic Fluorinating Reagents Synthetic Organic Chemistry Halogenation Fluorination Structure of Chemicals Quaternary Ammonium Compounds Ammonium Polyhalides, etc. (Quaternary)